Single-use bioreactor has many advantages comparing with the traditional stainless steel bioreactor : less initial investment, fast construction, high process flexibility; No online cleaning, in-place sterilization; Save time, reduce equipment space, reduce manpower and injection water; Suitable for MAH model and technology transfer. We offer two kinds of single-use bioreactors with suspension and adherent culture platforms: CUR series and CPB series.
CUR bioreactor adopts "Non-bubbling Interfacial Oxygen Transfer Mechanism" for oxygen transfer, which has high volumetric oxygen transfer coefficient.
Application: Cell suspension culture
Features and Advantages
Non-bubbling interface oxygen transfer mechanism, high oxygen transfer efficiency
No internal mixing impeller, extremely low shear forces
Easy to achieve high viable cell density and high viability, 108cells/ml achieved
Intelligent control system, simple operation interface
Additional connection interfaces (Open common communication interfaces to support signal docking with third-party systems)
Local online data monitor and control such as PH, DO, temperature and mixing speed, real-time data record , reports and curves can be generated.
Enable remote monitor and control of process parameters;
Culture of different cells
Batch culture of the following cell lines was performed in a CUR50 torrent reactor with maximum cell densities
| Cell Line |
Cell Density |
| CHO-S |
2.5×107 CHO-S cells/ml |
| BHK-21 |
3.0×107 BHK-21 cells/ml |
| CHO-K1 |
2.0×107 CHO-K1 cells/ml |
| SF9 (insect) |
1.8×107 SF9 (insect) cells/ml |
Application case 1 CHO cell suspension culture
Application case 2
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